e-ISSN 1694-2078
p-ISSN 1694-2086
 

Arch Med Biomed Res. 2016;3:39-51. doi:10.4314/ambr.v3i1.6

Ignatius Mzungu1, Helen I Inabo2, Stephen O Olonitola2, Maryam Aminu2

Author Affiliations

1Department of Biological Sciences, Federal University, Dutsin-Ma. Katsina State, Nigeria
2Department of Microbiology, Ahmadu Bello University, Zaria. Kaduna State, Nigeria

correspondence to
Ignatius Mzungu: imzungu@fudutsinma.edu.ng

Received: November 20, 2015
Revised: March 20, 2016
Accepted: March 21, 2016

Abstract

This study was conducted to assess the prevalence of Salmonella species among children having diarrhea in Katsina State, Nigeria. A total of 220 diarrhea stool samples of children aged five years and below (0-5 years) were collected and screened for Salmonella species using culture technique. Presumptively positive isolates were further screened biochemically and serologically, using MicrogenTM Enterobactericeae ID kit and MicrogenTM Salmonella rapid confirmatory latex agglutination test kit. Antibiotic susceptibility of confirmed isolates was carried out and resistance patterns of the isolates determined. The highest incidence was observed in children of 13-24 months of age and the least in children of 0-12 months of age. There was a higher prevalence in male than female children. All the isolates screened were resistant to Ampicillin and Amoxicillin and of these, 90.9% were resistant to Amoxicillin-clavulanic acid and 45.5% were resistant to Nalidixic acid. However, 100% were sensitive to Gentamicin, 90.9% were sensitive to Ciprofloxacin and Cefotaxime and 9.09% showed reduced susceptibility to Ciprofloxacin. Both the occurrence of Salmonella in children and their resistance to multiple antibiotics as observed are of public health significance. The vein of this study underscores the importance of routine monitoring of the incidence of Salmonella and continued health education of caregivers.

KEY WORDS: Antibiotic resistance; Prevalence of Salmonella; Childhood diarrhea; Katsina State; Antibiotics susceptibility of Salmonella

 

CrossRef Link

http://dx.doi.org/10.4314/ambr.v3i1.6

 
   
This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.